Support Us Button Widget

A new look for a Main Street building

Main Street Labs will have an updated, multi-facade appearance on South Main Street + West Washington Street.

GVL-MAIN STREET LABS RENDERING-SEPT 2022

One of three façades that will make up the exterior.

The City of Greenville Design Review Board Urban Panel unanimously approved the proposed exterior renovation designs for 2 N. Main St. (at the corner of Main and Washington Streets).

Animated GIF - Find & Share on GIPHY

The space — formerly a JCPenney in the 1940’s and ChartSpan in the 2010’s — houses Main Street Labs, a “biotech hub” for medical companies, like KIYATEC (a clinical stage cancer diagnostics company and the first tenant). Main Street Labs will also feature a retail shop + 100,000 sqft of lab space for future tenants.

The renovation of the entire exterior will be carried out in three sections — with the end result having the appearance of three different façades to break down the building’s scale to compliment smaller surrounding buildings.

You may be wondering, “What about Millie, the Mice on Main mouse in front of this building?” Don’t worry. Millie will be removed during construction for a “vacation.”

Click here for a detailed look at the plans.

More from GVLtoday
A new Wind Phone now offers visitors a quiet space in Conestee’s Rock Garden to share unspoken words with lost loved ones.
Greenville’s civic and business leaders are traveling to Boise, Idaho, for a multiday Intercommunity Leadership Visit — exploring how one of America’s top-ranked cities is tackling growth, innovation, and quality of life. We’re taking you along.
Once a 1929 synagogue, now a downtown retreat — 307 Townes Street blends history, craftsmanship, and modern luxury. From a dome-crowned primary suite to a garden oasis with a heated pool, this landmark home is on the market.
VisitGreenvilleSC shared new tourism figures, including tax relief it brings residents in and around Greenville.
Here’s how you can turn your old photos and records into a piece of Greenville history.
We think it might be time for GVL to get a flag of its own.
We’re sharing 10+ spots for watching sports in Greenville.
As “Top Chef” kicks off its filming, with plans to shoot in Greenville, alumni of the show and other fan-favorite television chefs are descending on our city for the 20th annual euphoria festival.
Directly north, east, south, and west of GVL, cities across the world await.
From Luke Bryan to The Lumineers, get your tickets to these upcoming concerts in Greenville before they sell out.