From boutique offices to standout retail, Greenville’s office vacancy remains competitive — making these spaces worth a closer look. Submit a listing below, or reply to this email to let us know what you want to see next.
Office
Office space, for lease | Falls Tower, 355 S. Main St. | 5,692 sqft | $47.50/sqft | Move-in ready, fully furnished office with private offices, conference rooms, open space, large break room, and double-door glass entrance.
Office condo, for sale | 233 N. Main St., Noma Flats | 1,620-3,353 sqft | $476,0000-$996,000 per unit | Rare opportunity in the central business district with private balconies, recently renovated exterior and common areas, covered walkway to city parking garage, and walkable access to 100+ restaurants, shops, and cultural venues.
Office space, for lease | 504 Rhett St. | 2,035–2,626 sqft | $34/sqft | Two move-in-ready suites are available in the West End, one block from Fluor Field and walkable to Unity Park, Falls Park, and the Swamp Rabbit Trail, featuring exterior signage, an outdoor patio, a fitness center, and on-site showers.
Office space, for lease | 200 S. Main St. | ~550 sqft | $750/month per office | Three private offices available in downtown, steps from City Hall, the Peace Center, Falls Park, and Camperdown Plaza, with parking available.
Retail
Retail space, for lease | Former Walgreens, 1801 Poinsett Hwy. | Call broker for rate | Prime retail location with high visibility, modern construction, adaptable for repurposing or build-to-suit, across from Cherrydale Point Shopping Mall.
Multi-use space, for sale | 205 N. Main St. | 4,008 sqft | $2.75 million ($646.21/sqft) | Prime downtown Main Street building across from Hyatt Hotel, heavy foot traffic, large display windows, three stories with top-floor residential/development opportunity.
Greenville Chamber honored the Upstate’s top business leaders at its 137th Annual Meeting.
Photo by GVLtoday
Quoted
“Greenville’s story has never been written by one person or one organization. It’s been written by generations of — people, visionaries, business owners, educators, and neighbors — partnering, believing, and building something extraordinary together.” That’s how Greenville Chamber President and CEO Carlos Phillips captured this year’s annual meeting theme: Greater Together. See who won awards.
Development
Court Street could soon be transformed. Design plans were approved for an eight-story building with street-level restaurants and retail and seven floors of offices. The 0.4-acre site neighbors 300 E. McBee Ave., and the city is also exploring a pedestrian-only section with an all-weather market and event space.
Announced
Plans are moving forward for an $18.4 million redevelopment of the former North Main Bi-Lo into Class A commercial space known as N. Main. Greenville City Council reviewed an abandoned-building designation tied to state tax credits, with a vote expected Monday, March 9. (Greenville Journal)
Development
Greenville City Council approved $3 million to kick off the long-planned City Hall renovation. The funding will cover design and engineering, with plans expected this spring. Construction on the 53-year-old Main Street building is slated to begin in early 2027 and take about 18 months. (Greenville Journal)
Announced
A new boutique hotel is proposed for downtown at 101 College St., replacing the former Cafe and Then Some while honoring its history as a comedy dinner theater and 1920s car dealership. The 17-room Banter Hotel would feature a restaurant, rooftop bar, and speakeasy. Plans are expected to go before the Greenville Design Review Board this April.
Job
Spartanburg Community College is seeking an Executive Director for its SCC Foundation. Lead fundraising strategy, major gifts, donor relations, and board engagement to advance the College’s mission. Full-time in Spartanburg County, with a salary range of $79,600–$130,000. Candidates should have proven experience in development, nonprofit leadership, or major gift fundraising.
Biz
Coastal Precast Systems is investing $9 million to open its first SC operation in Clinton, bringing 70 new jobs to Laurens County. The new facility will produce precast and prestressed concrete components for infrastructure projects across the Southeast, with operations expected to begin in Q3. (SC Biz)
Travel
Breeze Airways is expanding at Greenville-Spartanburg International Airport, adding flights to Fort Lauderdale (starting July 2, $49) and Cincinnati (starting July 3, $139). More direct flights make travel easier for business pros, improve client access, and open regional meeting opportunities. Heading out soon? Check our airport guide for tips. (Greenville News)
Thought Leadership
SkilRedi, a Clemson-born AI platform for technician training, took home the Small Business award at the 2025 InnoVision Awards. CEO Ben Dillard talks with Mike Switzer about the company’s innovation and next steps.
Biz
The 10th Annual VentureSouth Summit wrapped in Greenville last week, bringing over 200 angel investors, portfolio companies, and guests together for two days of pitches, panels, and networking. Highlights included portfolio reviews, lessons on entrepreneurial exits, and sports investing insights. Members can now evaluate 23 potential investment rounds as VentureSouth gears up for its 2027 summit.
Thought Leadership
Want to grow your investor network in 2026? Conferences are the secret weapon for founders — if you know how to prep, connect, and follow up. This playbook by The Startupverse shows how one event can turn into dozens of meaningful investor relationships.
Watch
In SCBIZ’s “10 Questions With…” series, Robin Gibson recently interviewed Garrett Stern, Executive Director of Furman University’s Center for Innovative Leadership, at the South Carolina Manufacturing Conference and Expo. The discussion highlights how the center helps organizations build innovative cultures, strengthen leadership, and upskill the workforce through hands-on, customizable programs.
Announced
Trueline’s founding presale is now live, offering a first look at The Green Room, a private members club inside the new West End venue. The launch comes amid major investment in Greenville’s live music scene, with Trueline slated to open later this year.
Pictured from left to right: Gary Daniels, Drew Bowland, Lizzie Bebber, Shane Kendrick, and Wes Lehrer.
Photo by Jack Robert Photography, courtesy of Huntington Bank
Huntington Bank celebrated the opening of its first Greenville branch and commercial office at 606 S. Main St. with a community launch on Feb. 26. The opening is part of the bank’s broader expansion across North and South Carolina. Local colleagues, community members, and Founders Circle guests gathered to mark the milestone and support the region, including a $10,000 donation to United Ministries.
Events
Agenda
Editor’s Picks
2026 SEC Women’s Basketball Tournament, Session 4 | Thursday, March 5 | 6 p.m. | Bon Secours Wellness Arena | $49 | Young Professionals Night brings together career-minded peers for a game-day experience with an exclusive panel featuring leaders in sports, wellness, and entertainment — plus drinks, a meal voucher, and reserved lower bowl seats.
International Women’s Day 2026: Give to Gain | Friday, March 6 | 8:30-11 a.m. | Flywheel Coworking Space | Free, reserve your spot | Celebrate International Women’s Day with Give to Gain, a peer coaching experience focused on connection, growth, and shared leadership insights.
I’ve got a reader-submitted small business spotlight for you.R. Cappelli, described as “Build-A-Bear, but for hats, fascinators, and purses,” celebrated its second anniversary on March 1. To mark the milestone, the Village of West Greenville location is hosting Derby-style fascinator workshops on Tuesday, March 10, and Friday, April 3. Hats off to two years.
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